Probably not; at least I shouldn't expect to. However, despite hypothermia, broken limbs and a pile of other problems, I can almost always make fire with just one working thumb and a lighter. That fire can keep me warm, signal for help, boil water and much more. Now, in an ideal situation, you'll have the knife…and at least two ways to make fire…and first aid gear…and some form of shelter. But if you have only one survival gear item, you'll be best off it it's a lighter.