Lay the hide open, flesh side up. Apply the solution directly from the bottle to the hide. Pour small amounts at a time onto the hide and use a large paintbrush to spread it around. If you're wearing gloves, you can simply use your hands. It's important to make sure you cover every bit of the flesh with the solution. Massage it in and fold the flesh sides together again. Leave overnight 12 hours and then open the hide and let it continue drying. Keep in mind that the formula has an odor. Although it's not totally bad (similar to musty wet leather), you'll want to keep the smell in mind when storing the hide during this process. It will quickly permeate a room. I suggest putting the hide in the garage, basement, or shed where no animals can get to it.